Incorporating prior knowledge into Gene Network Study

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Incorporating prior knowledge into Gene Network Study

MOTIVATION A major goal in genomic research is to identify genes that may jointly influence a biological response. From many years of intensive biomedical research, a large body of biological knowledge, or pathway information, has accumulated in available databases. There is a strong interest in leveraging these pathways to improve the statistical power and interpretability in studying gene net...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2013

ISSN: 1460-2059,1367-4803

DOI: 10.1093/bioinformatics/btt443